We are in relentless pursuit of breakthroughs that transform patients' lives. We drive innovation daily to make the world a more healthy place. This was Charles Pfizer's original vision, and it still holds true today. Evidence confirms what we instinctively know: that purpose-driven companies achieve more, are more innovative, recruit and maintain the best professionals, and know how to maximize the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—powers everything we do and reflects our passion for building on our legacy as one of the most important contributors of good to the world. Each word in our purpose has significance and reflects the value we strive to bring to patients and society. Our purpose makes certain that patients remain at the centre of all we do. We live our purpose by seeking the best science in the world, partnering with others in the healthcare system to enhance access to our medicines, employing digital technologies to improve our drug discovery and development, as well as patient outcomes, and spearheading the conversation to push for pro-innovation/pro-patient policies. Every choice we make, and every step we take is done with the patient in mind—and to create an environment where breakthroughs can prosper.