We are in relentless pursuit of breakthroughs that improve patients' lives. We create innovations every day to make the world a more healthy place. This was Charles Pfizer's original vision, and it still holds true today. Evidence confirms what intuition tells us: that purpose-driven companies deliver better results, are more creative, attract and retain the best professionals, and know how to unleash the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—powers everything we do and demonstrates our passion for building on our legacy as one of the most important contributors of good to the world. Each word in our purpose has importance and reflects the value we aim to bring to patients and society. Our purpose ensures that patients stay at the centre of all we do. We embody our purpose by sourcing the best science in the world, collaborating with others in the healthcare system to enhance access to our medicines, employing digital technologies to improve our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every choice we make, and every step we take is done with the patient in mind—and to nurture an environment where breakthroughs can flourish.