We are in constant pursuit of breakthroughs that improve patients' lives. We drive innovation each day to make the world a more healthy place. It was Charles Pfizer's initial vision, and it holds true today. Evidence confirms what intuition tells us: that purpose-driven companies deliver better results, are more inventive, draw and keep the best professionals, and know how to harness the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—powers everything we do and shows our passion for growing our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has meaning and embodies the value we aim to bring to patients and society. Our purpose makes certain that patients remain at the centre of all we do. We fulfill our purpose by finding the best science in the world, working with others in the healthcare system to improve access to our medicines, employing digital technologies to advance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can prosper.