We are in constant pursuit of breakthroughs that transform patients' lives. We innovate each day to make the world a healthier place. It was Charles Pfizer's original vision, and it still holds true today. Studies show what intuition tells us: that purpose-driven companies perform better, are more creative, recruit and maintain the best people, and know how to unleash the power of those individuals. Pfizer's purpose—Breakthroughs that transform patients' lives—fuels everything we do and shows our passion for building on our legacy as one of the most important contributors of good to the world. Each word in our purpose has significance and reflects the value we work to bring to patients and society. Our purpose makes certain that patients remain at the centre of all we do. We live our purpose by seeking the best science in the world, working with others in the healthcare system to increase access to our medicines, using digital technologies to advance our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every choice we make, and every step we take is done with the patient in mind—and to create an environment where breakthroughs can flourish.